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Comparative study of behavioural tests in the SOD1G93A mouse model of amyotrophic lateral sclerosis

In preclinical trials, a sensitive functional test is required to detect changes in the motor behaviour of the SOD1G93A mouse model of amyotrophic lateral sclerosis (ALS). We evaluated changes in body weight and motor impairment in behavioural tests, such as the rotarod, the hanging-wire test and th...

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Detalles Bibliográficos
Autores principales: OLIVÁN, Sara, CALVO, Ana Cristina, RANDO, Amaya, MUÑOZ, María Jesús, ZARAGOZA, Pilar, OSTA, Rosario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Association for Laboratory Animal Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427729/
https://www.ncbi.nlm.nih.gov/pubmed/25736480
http://dx.doi.org/10.1538/expanim.14-0077