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Development of a novel pink-eyed dilution mouse model showing progressive darkening of the eyes and coat hair with aging

Oca2(p-cas) (oculocutaneous albinism II; pink-eyed dilution castaneus) is a coat color mutant gene on mouse chromosome 7 that arose spontaneously in wild Mus musculus castaneus mice. Mice homozygous for Oca2(p-cas) usually exhibit pink eyes and gray coat hair on the non-agouti genetic background, an...

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Detalles Bibliográficos
Autores principales: ISHIKAWA, Akira, SUGIYAMA, Makoto, HONDO, Eiichi, KINOSHITA, Keiji, YAMAGISHI, Yuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Association for Laboratory Animal Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427736/
https://www.ncbi.nlm.nih.gov/pubmed/25739360
http://dx.doi.org/10.1538/expanim.14-0101