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Vitamin D Potentiates the Inhibitory Effect of MicroRNA-130a in Hepatitis C Virus Replication Independent of Type I Interferon Signaling Pathway

Calcitriol, the bioactive metabolite of vitamin D, was reported to inhibit HCV production in a synergistic fashion with interferon, a treatment in vitro. Our previous study established that miR-130a inhibits HCV replication by restoring the host innate immune response. We aimed to determine whether...

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Detalles Bibliográficos
Autores principales: Duan, Xiaoqiong, Guan, Yujuan, Li, Yujia, Chen, Shan, Li, Shilin, Chen, Limin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427768/
https://www.ncbi.nlm.nih.gov/pubmed/26060358
http://dx.doi.org/10.1155/2015/508989