Cargando…

Axonal autophagosomes recruit dynein for retrograde transport through fusion with late endosomes

Efficient degradation of autophagic vacuoles (AVs) via lysosomes is an important cellular homeostatic process. This is particularly challenging for neurons because mature acidic lysosomes are relatively enriched in the soma. Although dynein-driven retrograde transport of AVs was suggested, a fundame...

Descripción completa

Detalles Bibliográficos
Autores principales: Cheng, Xiu-Tang, Zhou, Bing, Lin, Mei-Yao, Cai, Qian, Sheng, Zu-Hang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427784/
https://www.ncbi.nlm.nih.gov/pubmed/25940348
http://dx.doi.org/10.1083/jcb.201412046