Cargando…
Axonal autophagosomes recruit dynein for retrograde transport through fusion with late endosomes
Efficient degradation of autophagic vacuoles (AVs) via lysosomes is an important cellular homeostatic process. This is particularly challenging for neurons because mature acidic lysosomes are relatively enriched in the soma. Although dynein-driven retrograde transport of AVs was suggested, a fundame...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2015
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427784/ https://www.ncbi.nlm.nih.gov/pubmed/25940348 http://dx.doi.org/10.1083/jcb.201412046 |