Rab27a controls HIV-1 assembly by regulating plasma membrane levels of phosphatidylinositol 4,5-bisphosphate

During the late stages of the HIV-1 replication cycle, the viral polyprotein Pr55(Gag) is recruited to the plasma membrane (PM), where it binds phosphatidylinositol 4,5-bisphosphate (PI(4,5)P(2)) and directs HIV-1 assembly. We show that Rab27a controls the trafficking of late endosomes carrying phos...

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Detalles Bibliográficos
Autores principales: Gerber, Pehuén Pereyra, Cabrini, Mercedes, Jancic, Carolina, Paoletti, Luciana, Banchio, Claudia, von Bilderling, Catalina, Sigaut, Lorena, Pietrasanta, Lía I., Duette, Gabriel, Freed, Eric O., de Saint Basile, Genevieve, Moita, Catarina Ferreira, Moita, Luis Ferreira, Amigorena, Sebastian, Benaroch, Philippe, Geffner, Jorge, Ostrowski, Matías
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427790/
https://www.ncbi.nlm.nih.gov/pubmed/25940347
http://dx.doi.org/10.1083/jcb.201409082

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427790/
https://www.ncbi.nlm.nih.gov/pubmed/25940347
http://dx.doi.org/10.1083/jcb.201409082

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