Cargando…
Nek5 promotes centrosome integrity in interphase and loss of centrosome cohesion in mitosis
Nek5 is a poorly characterized member of the NIMA-related kinase family, other members of which play roles in cell cycle progression and primary cilia function. Here, we show that Nek5, similar to Nek2, localizes to the proximal ends of centrioles. Depletion of Nek5 or overexpression of kinase-inact...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2015
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427792/ https://www.ncbi.nlm.nih.gov/pubmed/25963817 http://dx.doi.org/10.1083/jcb.201412099 |