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Synaptic vesicle release regulates the number of myelin sheaths made by individual oligodendrocytes in vivo

The myelination of axons by oligodendrocytes profoundly affects central nervous system function, but how this is regulated by neuronal activity in vivo is not known. Here we find that blocking synaptic vesicle release impairs CNS myelination by reducing the number of myelin sheaths made by individua...

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Detalles Bibliográficos
Autores principales: Mensch, Sigrid, Baraban, Marion, Almeida, Rafael, Czopka, Tim, Ausborn, Jessica, El Manira, Abdel, Lyons, David A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427868/
https://www.ncbi.nlm.nih.gov/pubmed/25849985
http://dx.doi.org/10.1038/nn.3991