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Synaptic vesicle release regulates the number of myelin sheaths made by individual oligodendrocytes in vivo
The myelination of axons by oligodendrocytes profoundly affects central nervous system function, but how this is regulated by neuronal activity in vivo is not known. Here we find that blocking synaptic vesicle release impairs CNS myelination by reducing the number of myelin sheaths made by individua...
Autores principales: | Mensch, Sigrid, Baraban, Marion, Almeida, Rafael, Czopka, Tim, Ausborn, Jessica, El Manira, Abdel, Lyons, David A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427868/ https://www.ncbi.nlm.nih.gov/pubmed/25849985 http://dx.doi.org/10.1038/nn.3991 |
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