Whole genome bisulfite sequencing of cell-free DNA and its cellular contributors uncovers placenta hypomethylated domains

BACKGROUND: Circulating cell-free fetal DNA has enabled non-invasive prenatal fetal aneuploidy testing without direct discrimination of the maternal and fetal DNA. Testing may be improved by specifically enriching the sample material for fetal DNA. DNA methylation may allow for such a separation of...

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Detalles Bibliográficos
Autores principales: Jensen, Taylor J, Kim, Sung K, Zhu, Zhanyang, Chin, Christine, Gebhard, Claudia, Lu, Tim, Deciu, Cosmin, van den Boom, Dirk, Ehrich, Mathias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427941/
https://www.ncbi.nlm.nih.gov/pubmed/25886572
http://dx.doi.org/10.1186/s13059-015-0645-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427941/
https://www.ncbi.nlm.nih.gov/pubmed/25886572
http://dx.doi.org/10.1186/s13059-015-0645-x

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