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A novel method for identifying disease associated protein complexes based on functional similarity protein complex networks

BACKGROUND: Protein complexes formed by non-covalent interaction among proteins play important roles in cellular functions. Computational and purification methods have been used to identify many protein complexes and their cellular functions. However, their roles in terms of causing disease have not...

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Detalles Bibliográficos
Autor principal: Le, Duc-Hau
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427953/
https://www.ncbi.nlm.nih.gov/pubmed/25969691
http://dx.doi.org/10.1186/s13015-015-0044-6