Soluble EpCAM levels in ascites correlate with positive cytology and neutralize catumaxomab activity in vitro

BACKGROUND: EpCAM is highly expressed on membrane of epithelial tumor cells and has been detected as soluble/secreted (sEpCAM) in serum of cancer patients. In this study we established an ELISA for in vitro diagnostics to measure sEpCAM concentrations in ascites. Moreover, we evaluated the influence...

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Detalles Bibliográficos
Autores principales: Seeber, Andreas, Martowicz, Agnieszka, Spizzo, Gilbert, Buratti, Thomas, Obrist, Peter, Fong, Dominic, Gastl, Guenther, Untergasser, Gerold
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427982/
https://www.ncbi.nlm.nih.gov/pubmed/25947366
http://dx.doi.org/10.1186/s12885-015-1371-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427982/
https://www.ncbi.nlm.nih.gov/pubmed/25947366
http://dx.doi.org/10.1186/s12885-015-1371-1

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