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Soluble EpCAM levels in ascites correlate with positive cytology and neutralize catumaxomab activity in vitro
BACKGROUND: EpCAM is highly expressed on membrane of epithelial tumor cells and has been detected as soluble/secreted (sEpCAM) in serum of cancer patients. In this study we established an ELISA for in vitro diagnostics to measure sEpCAM concentrations in ascites. Moreover, we evaluated the influence...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427982/ https://www.ncbi.nlm.nih.gov/pubmed/25947366 http://dx.doi.org/10.1186/s12885-015-1371-1 |