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Development of genetically engineered iNKT cells expressing TCRs specific for the M. tuberculosis 38-kDa antigen
INTRODUCTION: The invariant natural killer T (iNKT) cell has been shown to play a central role in early stages immune responses against Mycobacterium tuberculosis (Mtb) infection, which become nonresponsive (anergic) and fails to control the growth of Mtb in patients with active tuberculosis. Enhanc...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4428004/ https://www.ncbi.nlm.nih.gov/pubmed/25943357 http://dx.doi.org/10.1186/s12967-015-0502-4 |