Visualizing KcsA Conformational Changes upon Ion Binding by Infrared Spectroscopy and Atomistic Modeling

[Image: see text] The effect of ion binding in the selectivity filter of the potassium channel KcsA is investigated by combining amide I Fourier-transform infrared spectroscopy with structure-based spectral modeling. Experimental difference IR spectra between K(+)-bound KcsA and Na(+)-bound KcsA are...

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Detalles Bibliográficos
Autores principales: Stevenson, Paul, Götz, Christoph, Baiz, Carlos R., Akerboom, Jasper, Tokmakoff, Andrei, Vaziri, Alipasha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2015
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4428008/
https://www.ncbi.nlm.nih.gov/pubmed/25861001
http://dx.doi.org/10.1021/acs.jpcb.5b02223

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4428008/
https://www.ncbi.nlm.nih.gov/pubmed/25861001
http://dx.doi.org/10.1021/acs.jpcb.5b02223

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