Chromosome microduplication in somatic cells decreases the genetic stability of human reprogrammed somatic cells and results in pluripotent stem cells

Human pluripotent stem cells, including cloned embryonic and induced pluripotent stem cells, offer a limitless cellular source for regenerative medicine. However, their derivation efficiency is limited, and a large proportion of cells are arrested during reprogramming. In the current study, we explo...

Descripción completa

Detalles Bibliográficos
Autores principales: Yu, Yang, Chang, Liang, Zhao, Hongcui, Li, Rong, Fan, Yong, Qiao, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4428033/
https://www.ncbi.nlm.nih.gov/pubmed/25965553
http://dx.doi.org/10.1038/srep10114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4428033/
https://www.ncbi.nlm.nih.gov/pubmed/25965553
http://dx.doi.org/10.1038/srep10114

Ejemplares similares