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Chromosome microduplication in somatic cells decreases the genetic stability of human reprogrammed somatic cells and results in pluripotent stem cells
Human pluripotent stem cells, including cloned embryonic and induced pluripotent stem cells, offer a limitless cellular source for regenerative medicine. However, their derivation efficiency is limited, and a large proportion of cells are arrested during reprogramming. In the current study, we explo...
Autores principales: | Yu, Yang, Chang, Liang, Zhao, Hongcui, Li, Rong, Fan, Yong, Qiao, Jie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4428033/ https://www.ncbi.nlm.nih.gov/pubmed/25965553 http://dx.doi.org/10.1038/srep10114 |
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