Structural basis for epitope masking and strain specificity of a conserved epitope in an intrinsically disordered malaria vaccine candidate

Merozoite surface protein 2 (MSP2) is an intrinsically disordered, membrane-anchored antigen of the malaria parasite Plasmodium falciparum. MSP2 can elicit a protective, albeit strain-specific, antibody response in humans. Antibodies are generated to the conserved N- and C-terminal regions but many...

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Detalles Bibliográficos
Autores principales: Morales, Rodrigo A. V., MacRaild, Christopher A., Seow, Jeffrey, Krishnarjuna, Bankala, Drinkwater, Nyssa, Rouet, Romain, Anders, Robin F., Christ, Daniel, McGowan, Sheena, Norton, Raymond S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4428071/
https://www.ncbi.nlm.nih.gov/pubmed/25965408
http://dx.doi.org/10.1038/srep10103

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4428071/
https://www.ncbi.nlm.nih.gov/pubmed/25965408
http://dx.doi.org/10.1038/srep10103

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