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Establishment of a patient-derived orthotopic osteosarcoma mouse model

BACKGROUND: Osteosarcoma (OS) is the most common pediatric primary malignant bone tumor. As the prognosis for patients following standard treatment did not improve for almost three decades, functional preclinical models that closely reflect important clinical cancer characteristics are urgently need...

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Detalles Bibliográficos
Autores principales: Blattmann, Claudia, Thiemann, Markus, Stenzinger, Albrecht, Roth, Eva K, Dittmar, Anne, Witt, Hendrik, Lehner, Burkhard, Renker, Eva, Jugold, Manfred, Eichwald, Viktoria, Weichert, Wilko, Huber, Peter E, Kulozik, Andreas E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4428092/
https://www.ncbi.nlm.nih.gov/pubmed/25926029
http://dx.doi.org/10.1186/s12967-015-0497-x