Effectiveness of Shrinkage and Variable Selection Methods for the Prediction of Complex Human Traits using Data from Distantly Related Individuals

Genome‐wide association studies (GWAS) have detected large numbers of variants associated with complex human traits and diseases. However, the proportion of variance explained by GWAS‐significant single nucleotide polymorphisms has been usually small. This brought interest in the use of whole‐genome...

Descripción completa

Detalles Bibliográficos
Autores principales: Berger, Swetlana, Pérez‐Rodríguez, Paulino, Veturi, Yogasudha, Simianer, Henner, de los Campos, Gustavo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4428155/
https://www.ncbi.nlm.nih.gov/pubmed/25600682
http://dx.doi.org/10.1111/ahg.12099

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4428155/
https://www.ncbi.nlm.nih.gov/pubmed/25600682
http://dx.doi.org/10.1111/ahg.12099

Ejemplares similares