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Effectiveness of Shrinkage and Variable Selection Methods for the Prediction of Complex Human Traits using Data from Distantly Related Individuals
Genome‐wide association studies (GWAS) have detected large numbers of variants associated with complex human traits and diseases. However, the proportion of variance explained by GWAS‐significant single nucleotide polymorphisms has been usually small. This brought interest in the use of whole‐genome...
Autores principales: | Berger, Swetlana, Pérez‐Rodríguez, Paulino, Veturi, Yogasudha, Simianer, Henner, de los Campos, Gustavo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4428155/ https://www.ncbi.nlm.nih.gov/pubmed/25600682 http://dx.doi.org/10.1111/ahg.12099 |
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