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Estimation of the methylation pattern distribution from deep sequencing data

BACKGROUND: Bisulphite sequencing enables the detection of cytosine methylation. The sequence of the methylation states of cytosines on any given read forms a methylation pattern that carries substantially more information than merely studying the average methylation level at individual positions. I...

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Detalles Bibliográficos
Autores principales: Lin, Peijie, Forêt, Sylvain, Wilson, Susan R, Burden, Conrad J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4428226/
https://www.ncbi.nlm.nih.gov/pubmed/25943746
http://dx.doi.org/10.1186/s12859-015-0600-6