The AAA+ proteins Pontin and Reptin enter adult age: from understanding their basic biology to the identification of selective inhibitors

Pontin and Reptin are related partner proteins belonging to the AAA+ (ATPases Associated with various cellular Activities) family. They are implicated in multiple and seemingly unrelated processes encompassing the regulation of gene transcription, the remodeling of chromatin, DNA damage sensing and...

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Detalles Bibliográficos
Autores principales: Matias, Pedro M., Baek, Sung Hee, Bandeiras, Tiago M., Dutta, Anindya, Houry, Walid A., Llorca, Oscar, Rosenbaum, Jean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4428354/
https://www.ncbi.nlm.nih.gov/pubmed/25988184
http://dx.doi.org/10.3389/fmolb.2015.00017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4428354/
https://www.ncbi.nlm.nih.gov/pubmed/25988184
http://dx.doi.org/10.3389/fmolb.2015.00017

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