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The AAA+ proteins Pontin and Reptin enter adult age: from understanding their basic biology to the identification of selective inhibitors
Pontin and Reptin are related partner proteins belonging to the AAA+ (ATPases Associated with various cellular Activities) family. They are implicated in multiple and seemingly unrelated processes encompassing the regulation of gene transcription, the remodeling of chromatin, DNA damage sensing and...
Autores principales: | Matias, Pedro M., Baek, Sung Hee, Bandeiras, Tiago M., Dutta, Anindya, Houry, Walid A., Llorca, Oscar, Rosenbaum, Jean |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4428354/ https://www.ncbi.nlm.nih.gov/pubmed/25988184 http://dx.doi.org/10.3389/fmolb.2015.00017 |
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