Biochemical characterization of the interactions between doxorubicin and lipidic GM1 micelles with or without paclitaxel loading

Doxorubicin (Dox) is an anthracycline anticancer drug with high water solubility, whose use is limited primarily due to significant side effects. In this study it is shown that Dox interacts with monosialoglycosphingolipid (GM1) ganglioside micelles primarily through hydrophobic interactions indepen...

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Detalles Bibliográficos
Autores principales: Leonhard, Victoria, Alasino, Roxana V, Bianco, Ismael D, Garro, Ariel G, Heredia, Valeria, Beltramo, Dante M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4428378/
https://www.ncbi.nlm.nih.gov/pubmed/26005348
http://dx.doi.org/10.2147/IJN.S77153

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4428378/
https://www.ncbi.nlm.nih.gov/pubmed/26005348
http://dx.doi.org/10.2147/IJN.S77153

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