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Biochemical characterization of the interactions between doxorubicin and lipidic GM1 micelles with or without paclitaxel loading
Doxorubicin (Dox) is an anthracycline anticancer drug with high water solubility, whose use is limited primarily due to significant side effects. In this study it is shown that Dox interacts with monosialoglycosphingolipid (GM1) ganglioside micelles primarily through hydrophobic interactions indepen...
Autores principales: | Leonhard, Victoria, Alasino, Roxana V, Bianco, Ismael D, Garro, Ariel G, Heredia, Valeria, Beltramo, Dante M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4428378/ https://www.ncbi.nlm.nih.gov/pubmed/26005348 http://dx.doi.org/10.2147/IJN.S77153 |
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