Memory Impairment and Reduced Exploratory Behavior in Mice after Administration of Systemic Morphine

In the present study, the effects of morphine were examined on tests of spatial memory, object exploration, locomotion, and anxiety in male ICR mice. Administration of morphine (15 or 30 mg/kg, intraperitoneally (i.p.)) induced a significant decrease in Y-maze alternations compared to saline vehicle...

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Detalles Bibliográficos
Autores principales: Kitanaka, Junichi, Kitanaka, Nobue, Hall, F Scott, Fujii, Mei, Goto, Akiko, Kanda, Yusuke, Koizumi, Akira, Kuroiwa, Hirotoshi, Mibayashi, Satoko, Muranishi, Yumi, Otaki, Soichiro, Sumikawa, Minako, Tanaka, Koh-ichi, Nishiyama, Nobuyoshi, Uhl, George R, Takemura, Motohiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4428380/
https://www.ncbi.nlm.nih.gov/pubmed/25987850
http://dx.doi.org/10.4137/JEN.S25057

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4428380/
https://www.ncbi.nlm.nih.gov/pubmed/25987850
http://dx.doi.org/10.4137/JEN.S25057

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