Quantifying the role of chaperones in protein translocation by computational modeling

The molecular chaperone Hsp70 plays a central role in the import of cytoplasmic proteins into organelles, driving their translocation by binding them from the organellar interior. Starting from the experimentally-determined structure of the E. coli Hsp70, we computed, by means of molecular simulatio...

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Detalles Bibliográficos
Autores principales: Assenza, Salvatore, De Los Rios, Paolo, Barducci, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4428437/
https://www.ncbi.nlm.nih.gov/pubmed/25988176
http://dx.doi.org/10.3389/fmolb.2015.00008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4428437/
https://www.ncbi.nlm.nih.gov/pubmed/25988176
http://dx.doi.org/10.3389/fmolb.2015.00008

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