Cargando…

Mediation of organismal aging and somatic proteostasis by the germline

Experimental interventions that reduce reproduction cause an extension in lifespan. In invertebrates, such as Caenorhabditis elegans, the aging of the soma is regulated by signals from the germline. Indeed, ablation of germ cells significantly extends lifespan. Notably, germline-deficient animals ex...

Descripción completa

Detalles Bibliográficos
Autores principales: Khodakarami, Amirabbas, Saez, Isabel, Mels, Johanna, Vilchez, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4428440/
https://www.ncbi.nlm.nih.gov/pubmed/25988171
http://dx.doi.org/10.3389/fmolb.2015.00003