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Challenging muscle homeostasis uncovers novel chaperone interactions in Caenorhabditis elegans

Proteome stability is central to cellular function and the lifespan of an organism. This is apparent in muscle cells, where incorrect folding and assembly of the sarcomere contributes to disease and aging. Apart from the myosin-assembly factor UNC-45, the complete network of chaperones involved in a...

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Detalles Bibliográficos
Autores principales: Frumkin, Anna, Dror, Shiran, Pokrzywa, Wojciech, Bar-Lavan, Yael, Karady, Ido, Hoppe, Thorsten, Ben-Zvi, Anat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4428482/
https://www.ncbi.nlm.nih.gov/pubmed/25988162
http://dx.doi.org/10.3389/fmolb.2014.00021