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Challenging muscle homeostasis uncovers novel chaperone interactions in Caenorhabditis elegans
Proteome stability is central to cellular function and the lifespan of an organism. This is apparent in muscle cells, where incorrect folding and assembly of the sarcomere contributes to disease and aging. Apart from the myosin-assembly factor UNC-45, the complete network of chaperones involved in a...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4428482/ https://www.ncbi.nlm.nih.gov/pubmed/25988162 http://dx.doi.org/10.3389/fmolb.2014.00021 |