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Wrecked regulation of intrinsically disordered proteins in diseases: pathogenicity of deregulated regulators
Biologically active proteins without stable tertiary structure are common in all known proteomes. Functions of these intrinsically disordered proteins (IDPs) are typically related to regulation, signaling, and control. Cellular levels of these important regulators are tightly regulated by a variety...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4428494/ https://www.ncbi.nlm.nih.gov/pubmed/25988147 http://dx.doi.org/10.3389/fmolb.2014.00006 |