Structural mechanisms of chaperone mediated protein disaggregation

The ClpB/Hsp104 and Hsp70 classes of molecular chaperones use ATP hydrolysis to dissociate protein aggregates and complexes, and to move proteins through membranes. ClpB/Hsp104 are members of the AAA+ family of proteins which form ring-shaped hexamers. Loops lining the pore in the ring engage substr...

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Detalles Bibliográficos
Autor principal: Sousa, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4428496/
https://www.ncbi.nlm.nih.gov/pubmed/25988153
http://dx.doi.org/10.3389/fmolb.2014.00012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4428496/
https://www.ncbi.nlm.nih.gov/pubmed/25988153
http://dx.doi.org/10.3389/fmolb.2014.00012

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