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Colorectal cancer susceptibility: apparent gender-related modulation by ABCB1 gene polymorphisms
BACKGROUND: The ATP-binding cassette transporter B1 (ABCB1) gene codes for a membrane efflux pump localized in epithelial cells. Together with other Permeability-glycoproteins in the small and large intestine, its product represents a barrier against xenobiotics, bacterial toxins, drugs and other su...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4428509/ https://www.ncbi.nlm.nih.gov/pubmed/25355168 http://dx.doi.org/10.1186/s12929-014-0089-8 |