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Colorectal cancer susceptibility: apparent gender-related modulation by ABCB1 gene polymorphisms

BACKGROUND: The ATP-binding cassette transporter B1 (ABCB1) gene codes for a membrane efflux pump localized in epithelial cells. Together with other Permeability-glycoproteins in the small and large intestine, its product represents a barrier against xenobiotics, bacterial toxins, drugs and other su...

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Detalles Bibliográficos
Autores principales: Martinelli, Marcella, Scapoli, Luca, Cura, Francesca, Rodia, Maria Teresa, Ugolini, Giampaolo, Montroni, Isacco, Solmi, Rossella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4428509/
https://www.ncbi.nlm.nih.gov/pubmed/25355168
http://dx.doi.org/10.1186/s12929-014-0089-8