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The negative regulators of Wnt pathway—DACH1, DKK1, and WIF1 are methylated in oral and oropharyngeal cancer and WIF1 methylation predicts shorter survival

The deregulation of Wnt signaling has recently emerged as one of the drivers of head and neck cancers. This is frequently related to the methylation of several antagonists of this pathway. This study aimed at the assessment of the profile of methylation of Wnt pathway antagonists and the determinati...

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Detalles Bibliográficos
Autores principales: Paluszczak, Jarosław, Sarbak, Joanna, Kostrzewska-Poczekaj, Magdalena, Kiwerska, Katarzyna, Jarmuż-Szymczak, Małgorzata, Grenman, Reidar, Mielcarek-Kuchta, Daniela, Baer-Dubowska, Wanda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4428535/
https://www.ncbi.nlm.nih.gov/pubmed/25487617
http://dx.doi.org/10.1007/s13277-014-2913-x