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Hepatitis C Virus NS3 Mediated Microglial Inflammation via TLR2/TLR6 MyD88/NF-κB Pathway and Toll Like Receptor Ligand Treatment Furnished Immune Tolerance

BACKGROUND: Recent evidence suggests the neurotrophic potential of hepatitis C virus (HCV). HCV NS3 protein is one of the potent antigens of this virus mediating inflammatory response in different cell types. Microglia being the immune surveillance cells in the central nervous system (CNS), the infl...

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Detalles Bibliográficos
Autores principales: Rajalakshmy, Ayilam Ramachandran, Malathi, Jambulingam, Madhavan, Hajib Naraharirao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4428696/
https://www.ncbi.nlm.nih.gov/pubmed/25965265
http://dx.doi.org/10.1371/journal.pone.0125419