Cargando…

Hepatitis C Virus NS3 Mediated Microglial Inflammation via TLR2/TLR6 MyD88/NF-κB Pathway and Toll Like Receptor Ligand Treatment Furnished Immune Tolerance

BACKGROUND: Recent evidence suggests the neurotrophic potential of hepatitis C virus (HCV). HCV NS3 protein is one of the potent antigens of this virus mediating inflammatory response in different cell types. Microglia being the immune surveillance cells in the central nervous system (CNS), the infl...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rajalakshmy, Ayilam Ramachandran, Malathi, Jambulingam, Madhavan, Hajib Naraharirao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4428696/ https://www.ncbi.nlm.nih.gov/pubmed/25965265 http://dx.doi.org/10.1371/journal.pone.0125419

Ejemplares similares

Hepatitis C virus core and NS3 antigens induced conjunctival inflammation via toll-like receptor–mediated signaling
por: Rajalakshmy, Ayilam Ramachandran, et al.
Publicado: (2014)

MyD88 and TLR4 Expression in Epithelial Ovarian Cancer
por: Block, Matthew S., et al.
Publicado: (2018)

Inflammatory Role of TLR-MyD88 Signaling in Multiple Sclerosis
por: Zheng, Chao, et al.
Publicado: (2020)

Soyasaponins reduce inflammation by downregulating MyD88 expression and suppressing the recruitments of TLR4 and MyD88 into lipid rafts
por: Chen, Junbin, et al.
Publicado: (2020)

Draft genome sequence of bla(Veb-1), bla(oxa-10)producing multi-drug resistant (MDR) Pseudomonas aeruginosastrain VRFPA09 recovered from bloodstream infection
por: Murugan, Nandagopal, et al.
Publicado: (2015)

From monogenic lupus to TLR7/MyD88-targeted therapy
por: Wang, Min, et al.
Publicado: (2022)

Studies on New Delhi Metallo-Beta-Lactamse-1 producing Acinetobacter baumannii isolated from donor swab in a tertiary eye care centre, India and structural analysis of its antibiotic binding interactions
por: Sowmiya, Murali, et al.
Publicado: (2012)

Toll‐Like Receptor (TLR)4 and MyD88 are Essential for Atheroprotection by Peritoneal B1a B Cells
por: Hosseini, Hamid, et al.
Publicado: (2016)

Characterization of Antibiotic Resistance Profiles of Ocular Enterobacteriaceae Isolates
por: Paul-Satyaseela, Maneesh, et al.
Publicado: (2016)

TLR2 and TLR4 Mediate Differential Responses to Limb Ischemia through MyD88-Dependent and Independent Pathways
por: Sachdev, Ulka, et al.
Publicado: (2012)

TLR5 participates in the TLR4 receptor complex and promotes MyD88-dependent signaling in environmental lung injury
por: Hussain, Salik, et al.
Publicado: (2020)

Oxymatrine Downregulates TLR4, TLR2, MyD88, and NF-κB and Protects Rat Brains against Focal Ischemia
por: Fan, Hongguang, et al.
Publicado: (2009)

Exercise Therapy Downregulates the Overexpression of TLR4, TLR2, MyD88 and NF-κB after Cerebral Ischemia in Rats
por: Ma, Yuewen, et al.
Publicado: (2013)

Expression and significance of the TLR4/MyD88 signaling pathway in ovarian epithelial cancers
por: Kim, Ki Hyung, et al.
Publicado: (2012)

TLR4/MyD88 signaling determines the metastatic potential of breast cancer cells
por: Wu, Kunlin, et al.
Publicado: (2018)

TLR/MyD88-mediated Innate Immunity in Intestinal Graft-versus-Host Disease
por: Lee, Young-Kwan, et al.
Publicado: (2017)

Expression of TLR4-MyD88 and NF-κB in the Iris during Endotoxin-Induced Uveitis
por: Li, Shang, et al.
Publicado: (2010)

The Effect of TLR9, MyD88, and NF-κB p65 in Systemic Lupus Erythematosus
por: Wang, Huanan, et al.
Publicado: (2022)

TLR2, TLR4 and the MyD88 Signaling Are Crucial For the In Vivo Generation and the Longevity of Long-Lived Antibody-Secreting Cells
por: Komegae, Evilin Naname, et al.
Publicado: (2013)

TLR2, TLR4 AND MyD88 Mediate Allergic Airway Disease (AAD) and Streptococcus pneumoniae-Induced Suppression of AAD
por: Thorburn, Alison N., et al.
Publicado: (2016)

Mycobacterium tuberculosis Subverts the TLR-2 - MyD88 Pathway to Facilitate Its Translocation into the Cytosol
por: Rahman, Md. Aejazur, et al.
Publicado: (2014)

IRAK4 inhibition to shut down TLR signaling in autoimmunity and MyD88-dependent lymphomas
por: Küppers, Ralf
Publicado: (2015)

Regulator of calcineurin 1 differentially regulates TLR-dependent MyD88 and TRIF signaling pathways
por: Pang, Zheng, et al.
Publicado: (2018)

Selective disruption of TLR2-MyD88 interaction inhibits inflammation and attenuates Alzheimer’s pathology
por: Rangasamy, Suresh B., et al.
Publicado: (2018)

Enhanced Calvarial Bone Healing in CD11c-TLR4(−/−) and MyD88(−/−) Mice
por: Wang, Dan, et al.
Publicado: (2017)

The role of the MAD2-TLR4-MyD88 axis in paclitaxel resistance in ovarian cancer
por: Bates, Mark, et al.
Publicado: (2020)

Anaplasma phagocytophilum Induces TLR- and MyD88-Dependent Signaling in In Vitro Generated Murine Neutrophils
por: Müller, Beate J., et al.
Publicado: (2021)

Group A Streptococcus Activates Type I Interferon Production and MyD88-dependent Signaling without Involvement of TLR2, TLR4, and TLR9
por: Gratz, Nina, et al.
Publicado: (2008)

Mechanistic Studies of Gypenosides in Microglial State Transition and its Implications in Depression-Like Behaviors: Role of TLR4/MyD88/NF-κB Signaling
por: Cao, Li-Hua, et al.
Publicado: (2022)

Phycocyanin attenuates pulmonary fibrosis via the TLR2-MyD88-NF-κB signaling pathway
por: Li, Chengcheng, et al.
Publicado: (2017)

The role of TLR4/MyD88/NF‐κB pathway in periodontitis‐induced liver inflammation of rats
por: Yue, Yiyun, et al.
Publicado: (2020)

TLR3-Dependent Activation of TLR2 Endogenous Ligands via the MyD88 Signaling Pathway Augments the Innate Immune Response
por: Teixeira, Hellen S., et al.
Publicado: (2020)

Moderate hypothermia inhibits microglial activation after traumatic brain injury by modulating autophagy/apoptosis and the MyD88-dependent TLR4 signaling pathway
por: Zhang, Fengchen, et al.
Publicado: (2018)

Hyaluronan Signaling during Ozone-Induced Lung Injury Requires TLR4, MyD88, and TIRAP
por: Li, Zhuowei, et al.
Publicado: (2011)

Involvement of TLR7 MyD88-dependent signaling pathway in the pathogenesis of adult-onset Still's disease
por: Chen, Der-Yuan, et al.
Publicado: (2013)

Effects of porcine MyD88 knockdown on the expression of TLR4 pathway-related genes and proinflammatory cytokines
por: Dai, Chaohui, et al.
Publicado: (2016)

Loss of TLR4 in mouse Müller cells inhibits both MyD88-dependent and –independent signaling
por: Liu, Li, et al.
Publicado: (2017)

Innate Sensing through Mesenchymal TLR4/MyD88 Signals Promotes Spontaneous Intestinal Tumorigenesis
por: Koliaraki, Vasiliki, et al.
Publicado: (2019)

TLR4/MyD88 -mediated CCL2 production by lipopolysaccharide (endotoxin): Implications for metabolic inflammation
por: Akhter, Nadeem, et al.
Publicado: (2018)

Mycobacterium indicus pranii therapy induces tumor regression in MyD88- and TLR2-dependent manner
por: Kumar, Pawan, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_iofgeag55eh98c82miqsjghq93