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An Ex Vivo Model for Studying Hepatic Schistosomiasis and the Effect of Released Protein from Dying Eggs

BACKGROUND: We report the use of an ex vivo precision cut liver slice (PCLS) mouse model for studying hepatic schistosomiasis. In this system, liver tissue is unfixed, unfrozen, and alive for maintenance in culture and subsequent molecular analysis. METHODS AND FINDINGS: Using thick naive mouse live...

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Detalles Bibliográficos
Autores principales: Gobert, Geoffrey N., Nawaratna, Sujeevi K., Harvie, Marina, Ramm, Grant A., McManus, Donald P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4428699/
https://www.ncbi.nlm.nih.gov/pubmed/25965781
http://dx.doi.org/10.1371/journal.pntd.0003760