Preclinical Pharmacokinetic Evaluation of β-Lapachone: Characteristics of Oral Bioavailability and First-Pass Metabolism in Rats

β-Lapachone has drawn increasing attention as an anti-inflammatory and anti-cancer drug. However, its oral bioavailability has not been yet assessed, which might be useful to develop efficient dosage forms possibly required for non-clinical and clinical studies and future market. The aim of the pres...

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Detalles Bibliográficos
Autores principales: Kim, Iksoo, Kim, Hyeongmin, Ro, Jieun, Jo, Kanghee, Karki, Sandeep, Khadka, Prakash, Yun, Gyiae, Lee, Jaehwi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4428724/
https://www.ncbi.nlm.nih.gov/pubmed/25995830
http://dx.doi.org/10.4062/biomolther.2015.029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4428724/
https://www.ncbi.nlm.nih.gov/pubmed/25995830
http://dx.doi.org/10.4062/biomolther.2015.029

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