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Two-pore domain potassium channels enable action potential generation in the absence of voltage-gated potassium channels

In this study, we explored the possibility that two-pore domain potassium (K(2P)) channels are sufficient to support action potential (AP) generation in the absence of conventional voltage-gated potassium (K(V)) channels. Hodgkin–Huxley parameters were used to mimic the presence of voltage-gated sod...

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Detalles Bibliográficos
Autores principales: MacKenzie, Georgina, Franks, Nicholas P., Brickley, Stephen G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4428809/
https://www.ncbi.nlm.nih.gov/pubmed/25482670
http://dx.doi.org/10.1007/s00424-014-1660-6