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Side-Chain Cysteine-Functionalized Poly(2-oxazoline)s for Multiple Peptide Conjugation by Native Chemical Ligation

[Image: see text] We prepared statistical copolymers composed of 2-methyl-2-oxazoline (MeOx) in combination with 2-butenyl-2-oxazoline (BuOx) or 2-decenyl-2-oxazoline (DecOx) as a basis for polymer analogous introduction of 1,2-aminothiol moieties at the side chain. MeOx provides hydrophilicity as w...

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Detalles Bibliográficos
Autores principales: Schmitz, Michael, Kuhlmann, Matthias, Reimann, Oliver, Hackenberger, Christian P. R., Groll, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2015
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4428813/
https://www.ncbi.nlm.nih.gov/pubmed/25728550
http://dx.doi.org/10.1021/bm501697t