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Nano-LC-MS/MS for Quantification of Lyso-Gb3 and Its Analogues Reveals a Useful Biomarker for Fabry Disease

Biomarkers useful for diagnosis and evaluation of treatment for patients with Fabry disease are urgently needed. Recently, plasma globotriaosylsphingosine (lyso-Gb3) and lyso-Gb3-related analogues have attracted attention as promising biomarkers of Fabry disease. However, the plasma concentrations o...

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Detalles Bibliográficos
Autores principales: Sueoka, Hideaki, Ichihara, Junji, Tsukimura, Takahiro, Togawa, Tadayasu, Sakuraba, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4428877/
https://www.ncbi.nlm.nih.gov/pubmed/25965380
http://dx.doi.org/10.1371/journal.pone.0127048