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The Brain Response to Peripheral Insulin Declines with Age: A Contribution of the Blood-Brain Barrier?
OBJECTIVES: It is a matter of debate whether impaired insulin action originates from a defect at the neural level or impaired transport of the hormone into the brain. In this study, we aimed to investigate the effect of aging on insulin concentrations in the periphery and the central nervous system...
Autores principales: | Sartorius, Tina, Peter, Andreas, Heni, Martin, Maetzler, Walter, Fritsche, Andreas, Häring, Hans-Ulrich, Hennige, Anita M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429020/ https://www.ncbi.nlm.nih.gov/pubmed/25965336 http://dx.doi.org/10.1371/journal.pone.0126804 |
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