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B Cell Production of Both OPG and RANKL is Significantly Increased in Aged Mice

Aging is a risk factor for osteoclastic bone loss and bone fracture. Receptor activator of NF-κB ligand (RANKL) is the key effector cytokine for osteoclastogenesis and bone resorption, and is moderated by its decoy receptor osteoprotegerin (OPG). The development of an inflammatory environment during...

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Detalles Bibliográficos
Autores principales: Li, Yan, Terauchi, Masakazu, Vikulina, Tatyana, Roser-Page, Susanne, Weitzmann, M. N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429037/
https://www.ncbi.nlm.nih.gov/pubmed/25984250
http://dx.doi.org/10.2174/1876525401406010008