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Identification of genes and gene pathways associated with major depressive disorder by integrative brain analysis of rat and human prefrontal cortex transcriptomes

Despite moderate heritability estimates, progress in uncovering the molecular substrate underpinning major depressive disorder (MDD) has been slow. In this study, we used prefrontal cortex (PFC) gene expression from a genetic rat model of MDD to inform probe set prioritization in PFC in a human post...

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Detalles Bibliográficos
Autores principales: Malki, K, Pain, O, Tosto, M G, Du Rietz, E, Carboni, L, Schalkwyk, L C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429169/
https://www.ncbi.nlm.nih.gov/pubmed/25734512
http://dx.doi.org/10.1038/tp.2015.15