A Case of Diverticular Perforation in a Young Patient with Rheumatoid Arthritis on Methotrexate

Background. Disease-modifying antirheumatic drugs (DMARDs), such as methotrexate (MTX), are associated with gastrointestinal toxicity. MTX inhibits dihydrofolate reductase, but it is unclear if polymorphisms of the methylenetetrahydrofolate reductase (MTHFR) gene predict toxicity. Case. We describe...

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Detalles Bibliográficos
Autores principales: Chang, Ian, Guggenheim, Carla, Laird-Fick, Heather
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429201/
https://www.ncbi.nlm.nih.gov/pubmed/26064129
http://dx.doi.org/10.1155/2015/617268

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429201/
https://www.ncbi.nlm.nih.gov/pubmed/26064129
http://dx.doi.org/10.1155/2015/617268

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