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A Case of Diverticular Perforation in a Young Patient with Rheumatoid Arthritis on Methotrexate
Background. Disease-modifying antirheumatic drugs (DMARDs), such as methotrexate (MTX), are associated with gastrointestinal toxicity. MTX inhibits dihydrofolate reductase, but it is unclear if polymorphisms of the methylenetetrahydrofolate reductase (MTHFR) gene predict toxicity. Case. We describe...
Autores principales: | Chang, Ian, Guggenheim, Carla, Laird-Fick, Heather |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429201/ https://www.ncbi.nlm.nih.gov/pubmed/26064129 http://dx.doi.org/10.1155/2015/617268 |
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