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Modeling drug resistance in a conjoint normal-tumor setting

BACKGROUND: In this paper, we modify our previously developed conjoint tumor-normal cell model in order to make a distinction between tumor cells that are responsive to chemotherapy and those that may show resistance. RESULTS: Using this newly developed core model, the evolution of three cell types:...

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Detalles Bibliográficos
Autores principales: Feizabadi, Mitra Shojania, Witten, Tarynn M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429337/
https://www.ncbi.nlm.nih.gov/pubmed/25588472
http://dx.doi.org/10.1186/1742-4682-12-3