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Modeling drug resistance in a conjoint normal-tumor setting
BACKGROUND: In this paper, we modify our previously developed conjoint tumor-normal cell model in order to make a distinction between tumor cells that are responsive to chemotherapy and those that may show resistance. RESULTS: Using this newly developed core model, the evolution of three cell types:...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429337/ https://www.ncbi.nlm.nih.gov/pubmed/25588472 http://dx.doi.org/10.1186/1742-4682-12-3 |