Palmitoylation of LIM Kinase-1 ensures spine-specific actin polymerization and morphological plasticity

Precise regulation of the dendritic spine actin cytoskeleton is critical for neurodevelopment and neuronal plasticity, but how neurons spatially control actin dynamics is not well defined. Here, we identify direct palmitoylation of the actin regulator LIM kinase-1 (LIMK1) as a novel mechanism to con...

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Detalles Bibliográficos
Autores principales: George, Joju, Soares, Cary, Montersino, Audrey, Beique, Jean-Claude, Thomas, Gareth M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429338/
https://www.ncbi.nlm.nih.gov/pubmed/25884247
http://dx.doi.org/10.7554/eLife.06327

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429338/
https://www.ncbi.nlm.nih.gov/pubmed/25884247
http://dx.doi.org/10.7554/eLife.06327

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