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Drug repositioning can accelerate discovery of pharmacological chaperones

A promising strategy for the treatment of genetic diseases, pharmacological chaperone therapy, has been proposed recently. It exploits small molecules which can be administered orally, reach difficult tissues such as the brain and have low cost. This strategy has a vast field of application. In orde...

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Detalles Bibliográficos
Autores principales: Hay Mele, Bruno, Citro, Valentina, Andreotti, Giuseppina, Cubellis, Maria Vittoria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429356/
https://www.ncbi.nlm.nih.gov/pubmed/25947946
http://dx.doi.org/10.1186/s13023-015-0273-2